Trust and obfuscation principles for quality of information in emerging pervasive environments

Non peer reviewedPostprin

Energy Minimization of System Pipelines Using Multiple Voltages

Modem computer and communication system design has to consider the timing constraints imposed by communication and system pipelines, and minimize the energy consumption. We adopt the recent proposed model for communication pipeline latency[23] and address the problem of how to minimize the power consumption in system-level pipelines under the latency constraints by selecting supply voltage for each pipeline stage using the variable voltage core-based system design methodology[l 11. We define the problem, solve it optimally under realistic assumptions and develop algorithms for power minimization of system pipeline designs based on our theoretical results. We apply this new approach on the 4- stage Myrinet GAM pipeline, with the appropriate voltage profiles, we achieve 93.4%, 91.3% and 26.9% power reduction on three pipeline stages over the traditional design

Synthesis Techniques for Low-Power Hard Real-Time Systems on Variable Voltage Processors

The energy efficiency of systems-on-a-chip can be much improved if one were to vary the supply voltage dynamically at run time. In this paper we describe the synthesis of systems-on-a-chip based on core processors, while treating voltage (and correspondingly, the clock frequency) as a variable to be scheduled along with the computation tasks during the static scheduling step. In addition to describing the complete synthesis design flow for these variable voltage systems, we focus on the problem of doing the voltage scheduling while taking into account the inherent limitation on the rates at which the voltage and clock frequency can be changed by the power supply controllers and clock generators. Taking these limits on rate of change into account is crucial since changing the voltage by even a volt may take time equivalent to 100s to 10,000s of instructions on modern processors. We present both an exact but impractical formulation of this scheduling problem as a set of non-linear equations, as well as a heuristic approach based on reduction to an optimally solvable restricted ordered scheduling problem. Using various task mixes drawn from a set of nine real-life applications, our results show that we are able to reduce power consumption to within 7% of the lower bound obtained by imposing no limit at the rate of change of voltage and clock frequencies

Corrosion behavior of ultrafine-grained AA2024 aluminum alloy produced by cryorolling.

The objectives of this study were to produce ultrafine-grained (UFG) AA2024 aluminum alloy by cryorolling followed by aging and to evaluate its corrosion behavior. Solutionized samples were cryorolled to ~85% reduction in thickness. Subsequent aging resulted in a UFG structure with finer precipitates of Al2CuMg in the cryorolled alloy. The (1) solutionized and (2) solutionized and cryorolled samples were uniformly aged at 160°C/24 h and were designated as CGPA and CRPA, respectively; these samples were subsequently subjected to corrosion studies. Potentiodynamic polarization studies in 3.5wt% NaCl solution indicated an increase in corrosion potential and a decrease in corrosion current density for CRPA compared to CGPA. In the case of CRPA, electrochemical impedance spectroscopic studies indicated the presence of two complex passive oxide layers with a higher charge transfer resistance and lower mass loss during intergranular corrosion tests. The improved corrosion resistance of CRPA was mainly attributed to its UFG structure, uniform distribution of fine precipitates, and absence of coarse grain-boundary precipitation and associated precipitate-free zones as compared with the CGPA alloy

A system architecture for exploiting mission information requirement and resource allocation

In a military scenario, commanders need to determine what kinds of information will help them execute missions. The amount of information available to support each mission is constrained by the availability of information assets. For example, there may be limits on the numbers of sensors that can be deployed to cover a certain area, and limits on the bandwidth available to collect data from those sensors for processing. Therefore, options for satisfying information requirements should take into consideration constraints on the underlying information assets, which in certain cases could simultaneously support multiple missions. In this paper, we propose a system architecture for modeling missions and allocating information assets among them. We model a mission as a graph of tasks with temporal and probabilistic relations. Each task requires some information provided by the information assets. Our system suggests which information assets should be allocated among missions. Missions are compatible with each other if their needs do not exceed the limits of the information assets; otherwise, feedback is sent to the commander indicating information requirements need to be adjusted. The decision loop will eventually converge and the utilization of the resources is maximized

Coordinated Static and Mobile Sensing for Environmental Monitoring

Distributed embedded sensor networks are now being successfully deployed in environmental monitoring of natural phenomena as well as for applications in commerce and physical security. While substantial progress in sensor network performance has appeared, new challenges have also emerged as these systems have been deployed in the natural environment. First, in order to achieve minimum sensing fidelity performance, the rapid spatiotemporal variation of environmental phenomena requires impractical deployment densities. The presence of obstacles in the environment introduces sensing uncertainty and degrades the performance of sensor fusion systems in particular for the many new applications of image sensing. The physical obstacles encountered by sensing may be circumvented by a new mobile sensing method or Networked Infomechanical Systems (NIMS). NIMS integrates distributed, embedded sensing and computing systems with infrastructure-supported mobility. NIMS now includes coordinated mobility methods that exploits adaptive articulation of sensor perspective and location as well as management of sensor population to provide the greatest certainty in sensor fusion results. The architecture, applications, and implementation of NIMS will be discussed here. In addition, results of environmentally-adaptive sampling, and direct measurement of sensing uncertainty will be described

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.

Approaches in biotechnological applications of natural polymers

Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them are reviewed in this article.. }To the Conselho Nacional de Desenvolvimento Cientfíico e Tecnológico (CNPq) for fellowships (LCBBC and MGCC) and the Coordenação de Aperfeiçoamento de Pessoal de Nvíel Superior (CAPES) (PBSA). This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and COMPETE 2020 (POCI-01-0145-FEDER-006684) (JAT)